Acne won't go away?

The following individuals cannot be prescribed isotretinoin: • Women who are pregnant, may be pregnant, or are planning to become pregnant • Women who are breastfeeding • Individuals under 15 years of age or still growing in height • Those currently taking tetracycline-class antibiotics (e.g., Minocin, Minocycline, Vibramycin) • Those being treated for depression or other psychiatric conditions • Those with liver dysfunction • Those with elevated triglycerides or cholesterol • Those with hypervitaminosis A

【Critical Warning】 Isotretinoin may cause miscarriage or birth defects if taken during pregnancy. Strict contraception is required during the treatment period, for 1 month prior to starting, and for 6 months after completing treatment. 【Common Side Effects】 Dry lips, dry skin 【Rare Side Effects】 Headache, rash, mild itching, skin peeling, blepharitis, conjunctivitis, muscle/joint pain, decreased liver function, hair thinning, dizziness, nausea, depression, psychosis (hallucinations), self-harm ideation, and other serious psychiatric conditions. *These rare side effects have almost never been observed at our clinic.

【Unapproved Medication Disclosure】 Isotretinoin is not approved for domestic use in Japan. ■ Source Imported by our clinic physicians under Japan's personal import framework. For more information on unapproved medications imported personally, please refer to the MHLW website. ■ Domestically approved alternatives There are no domestically approved medications with the same active ingredient. ■ International safety information See "Side Effects" section above. ■ Adverse Drug Reaction Relief System In the unlikely event of severe side effects, this medication is NOT covered by Japan's Adverse Drug Reaction Relief System, as it is an unapproved drug.